San Diego, CA, United States of America

Padmanabh Chivukula

USPTO Granted Patents = 51 

 

 

Average Co-Inventor Count = 3.3

ph-index = 10

Forward Citations = 241(Granted Patents)

Forward Citations (Not Self Cited) = 97(Dec 10, 2025)


Location History:

  • La Jolla, CA (US) (2022)
  • San Diego, CA (US) (2016 - 2024)

Company Filing History:


Years Active: 2016-2025

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Areas of Expertise:
Ionizable Cationic Lipid
RNA Delivery
Lipid-Encapsulated RNA Nanoparticles
Immune Responses
Coronavirus Vaccine Compositions
Nucleic Acid Delivery
Therapeutic Oligomers
Gene Editing
Aromatic Ionizable Cationic Lipid
Cystic Fibrosis Treatment
Hepatitis B Virus
Amyloidosis Treatment
51 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Padmanabh Chivukula

Introduction: Padmanabh Chivukula, based in San Diego, CA, is a prominent inventor with an impressive portfolio of 45 patents. His work primarily focuses on advanced biomedical technologies, particularly in the realm of RNA nanoparticles and vaccine development, placing him at the forefront of innovation in these critical areas.

Latest Patents: Among his latest inventions is a groundbreaking method for creating lipid-encapsulated RNA nanoparticles. This method includes a series of precise steps: first, an aqueous solution that contains RNA flows through a tube with an inner diameter (ID) of about 0.1″ to 0.132″. Simultaneously, an ethanol solution containing lipids, including a cationic lipid, is introduced through a second tube with an ID of 0.005″ to 0.02″ at one-third the flow rate of the aqueous solution. These solutions are mixed in a specialized module, resulting in a turbulent flow that produces lipid-encapsulated RNA nanoparticles with a unique bilayer structure.

Additionally, Chivukula has developed significant contributions to coronavirus vaccine compositions and methods. His patents encompass nucleic acid molecules that encode viral replication proteins along with antigenic coronavirus proteins. The compositions derived from these nucleic acids are designed to effectively induce immune responses, reinforcing the potential of his innovations in combating viral diseases.

Career Highlights: Throughout his career, Padmanabh Chivukula has been associated with several influential companies, including Arcturus Therapeutics, Inc., and Arcturus, Inc. His work has not only contributed to advancements in therapeutic technologies but has also established him as a key figure within the biotechnology sector.

Collaborations: Chivukula’s innovative endeavors have seen him collaborate with esteemed colleagues such as Joseph E. Payne and Kiyoshi Tachikawa. These partnerships have been instrumental in driving forward his research goals and expanding the impact of his inventions within the scientific community.

Conclusion: Padmanabh Chivukula exemplifies the spirit of innovation in biotechnology, with a significant body of work that continues to contribute to the fields of RNA technology and vaccine development. With his extensive patent portfolio and collaborative research, he stands as a testament to the role of inventors in shaping a healthier future through groundbreaking scientific advancements.

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