Location History:
- Chapel Hill, NC (US) (1998 - 2002)
- Moncure, NC (US) (1999 - 2009)
Company Filing History:
7 out of 1,271 
1 out of 22 Years Active: 1998-2009
Title: Inventor P Frederick Sparling: Innovations in Iron-Regulated Proteins
Introduction
P Frederick Sparling is a notable inventor based in Moncure, North Carolina, recognized for his significant contributions to the field of biochemistry with a focus on iron-regulated proteins. With a total of eight patents to his name, Sparling has been instrumental in advancing our understanding of essential biological functions.
Latest Patents
His latest patents include groundbreaking research on iron-regulated outer membrane proteins that play a critical role in transferrin receptor function. These proteins can be isolated using a transferrin affinity column and specifically bind to antisera raised against an iron-regulated outer membrane protein with a molecular weight of approximately 100 kD, found in antigenic iron-repressible proteins related to the hemolysin family of toxins. Furthermore, he has also developed an isolated antigenic polypeptide that consists of a segment containing at least fifty amino acid residues, which presents a unique amino acid sequence that is homologous yet distinct from segments in other members of the hemolysin family of toxins.
Career Highlights
Sparling has held positions at esteemed institutions, including the University of North Carolina at Chapel Hill and Imclone Systems, Inc. His work in these organizations has significantly impacted the research landscape, allowing for advancements in understanding proteins relevant to infectious diseases.
Collaborations
Throughout his career, P Frederick Sparling has collaborated with prominent scientists, including Nicholas H Carbonetti and Cynthia Nau Cornelissen. These collaborations have enhanced the scope of his research, contributing to vital discoveries in the biology of outer membrane proteins.
Conclusion
P Frederick Sparling's patents and research have positioned him as a key figure in the study of iron-regulated proteins. His commitment to innovation continues to influence the biochemistry field, paving the way for future advancements in medical science. As more discoveries are made, the significance of his work will undoubtedly lead to further breakthroughs in understanding protein functions and their applications in healthcare.