Berlin, Germany

Otto Engelfried


Average Co-Inventor Count = 4.2

ph-index = 4

Forward Citations = 48(Granted Patents)


Company Filing History:


Years Active: 1976-1978

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5 patents (USPTO):Explore Patents

Title: The Innovations of Inventor Otto Engelfried

Introduction: Otto Engelfried is a notable inventor based in Berlin, Germany, recognized for his significant contributions to the field of steroid chemistry. With five patents to his name, Engelfried has pioneered innovative methods for producing complex steroid structures, emphasizing both efficacy and the advancement of pharmaceutical sciences.

Latest Patents: Engelfried’s latest patents focus on the development of Δ9(11)-5α-D-homo-20-keto steroids and their derivatives. Specifically, his work involves the production of 3α-Hydroxy and 3α-acyloxy-Δ9(11)-5α-D-homo-20-ketopregnenes through a intricate process of esterification and chlorination. The method includes esterifying a 3β-hydroxy-5α-20-keto pregnane with m-iodobenzoic acid, chlorinizing the resultant esters, and subsequently treating the products to yield the desired steroid compounds. This innovative approach offers new pathways to synthesizing potent steroid derivatives that have potential therapeutic applications.

Career Highlights: Otto Engelfried has made an indelible mark during his career at Schering Aktiengesellschaft, where he focuses on the intersection of chemistry and medicine. His inventive techniques have not only expanded the realm of steroid research but have also laid the groundwork for future innovations in the pharmaceutical industry.

Collaborations: Throughout his career, Engelfried has collaborated with esteemed colleagues such as Ulrich Kerb and Rudolf Wiechert. Together, they have contributed to the advancement of steroid research, fostering a dynamic environment of creativity and innovation within their team.

Conclusion: Otto Engelfried exemplifies the spirit of innovation within the realm of steroid research. Through his patents and collaborations, he has significantly contributed to the understanding and application of steroid derivatives, driving forward the boundaries of pharmaceutical chemistry. His work continues to influence the industry, highlighting the importance of inventive thinking in the realm of scientific exploration.

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