Company Filing History:
Years Active: 2001
Title: Otho Ulrich: Innovator in Molecular Measurement Technology
Introduction
Otho Ulrich is a notable inventor based in Ann Arbor, MI (US). He has made significant contributions to the field of molecular measurement technology, particularly through his innovative patent that addresses the binding interactions between proteins and nucleotides. His work has implications for various applications in pharmaceuticals and biological research.
Latest Patents
Otho Ulrich holds a patent for a "Method and apparatus for measurement of binding between a protein and a nucleotide." This invention presents a method and apparatus designed to measure the binding interactions between two types of molecules. The apparatus utilizes a sensor with a waveguide that has features resembling the first type of molecules. Light is injected into the waveguide to create an evanescent field at its surface. The second type of molecules is tagged with a chemical that alters light characteristics when it passes through. This setup allows for rapid monitoring of optical signal changes as binding occurs, enabling direct measurement of binding and dissociation rates. The data obtained can be used to compute various affinity constants and kinetic parameters for the molecular pair.
Career Highlights
Otho Ulrich is associated with Ia, Inc., where he continues to develop and refine his innovative technologies. His work has been instrumental in advancing the understanding of molecular interactions, particularly in the context of biological receptors and their nuclear response elements.
Collaborations
Otho has collaborated with notable colleagues, including Judith Louise Erb and James G Downward, IV. These collaborations have further enriched his research and development efforts in the field.
Conclusion
Otho Ulrich's contributions to molecular measurement technology highlight his innovative spirit and dedication to advancing scientific understanding. His patent serves as a valuable tool for researchers in various fields, particularly in the assessment of pharmaceuticals and biological interactions.