Company Filing History:
1 out of 832,812 Years Active: 2002
Title: Innovations in Dengue Vaccine Development by Osvaldo Reyes Acosta
Introduction
Osvaldo Reyes Acosta is an innovative inventor based in Habana, Cuba, known for his significant contributions to the field of biotechnology, particularly in developing synthetic peptides for dengue virus research. His work focuses on enhancing immune responses through the design of synthetic peptides, which are critical in the fight against dengue fever.
Latest Patents
Reyes Acosta holds a patent for the invention titled "Pre-M/M epitopes of dengue virus, synthetic peptides, chimeric proteins and their use." This patent describes five synthetic peptides derived from the pre-M/M protein of the Dengue-2 virus, corresponding to specific amino acid sequences (3-31, 45-67, 57-92, 69-93, and 103-124). The invention addresses the evaluation of the anti-peptide immune response in mice, indicating the potential for developing effective vaccines against dengue fever.
Career Highlights
Reyes Acosta's innovative work includes the development of recombinant fusion proteins that incorporate regions of the pre-M/M protein, showcasing his expertise in the field. His research highlights the presence of B cell epitopes in both mice and humans. Notably, the peptides he designed, specifically peptides 3-31 and 103-124, have been shown to elicit neutralizing antibodies against all four serotypes of the dengue virus, marking a significant advancement in medical research.
Collaborations
Throughout his career, Osvaldo Reyes Acosta has collaborated with talented colleagues, including Susana Vazquez Ramudo and Guadalupe Guzman Tirado. These collaborations have enriched his research and facilitated advancements in their shared objectives of combating dengue virus infections.
Conclusion
Osvaldo Reyes Acosta is a prominent figure in the field of dengue virus research, with a focused approach on synthetic peptides and their immune response capabilities. His patent and collaborative efforts contribute significantly to the ongoing endeavor to develop effective vaccines and therapeutic strategies against dengue fever, underscoring the importance of innovations in addressing global health challenges.