Location History:
- Tübgingen, DE (2007 - 2010)
- Tuebingen, DE (2008 - 2010)
- Tubingen, DE (2011)
Company Filing History:
Years Active: 2007-2011
Title: Innovations of Olaf Heidenreich
Introduction
Olaf Heidenreich is a notable inventor based in Tübingen, Germany. He has made significant contributions to the field of molecular biology, particularly in the area of RNA interference (RNAi). With a total of five patents to his name, Heidenreich's work has the potential to impact therapeutic approaches for various diseases.
Latest Patents
One of his latest patents is titled "RNAi modulation of MLL-AF4 and uses thereof." This invention relates to compositions and methods for modulating the expression of the MLL-AF4 fusion gene. More specifically, it focuses on the downregulation of MLL-AF4 by chemically modified oligonucleotides. Another significant patent is "Double-stranded RNA (dsRNA) and method of use for inhibiting expression of a fusion gene." This invention pertains to the specific inhibition of expression of a fusion gene in mammals using a short double-stranded RNA. The dsRNA is approximately 19-24 nucleotides in length and has a nucleotide sequence complementary to at least a part of the target gene. The dsRNAs developed in this patent are particularly useful for treating diseases caused by chromosomal aberrations, especially malignant diseases such as lymphoma and leukemia.
Career Highlights
Throughout his career, Olaf Heidenreich has worked with prominent companies in the biotechnology sector. Notably, he has been associated with Alnylam Pharmaceuticals, Inc. and Alnylam Europe AG. His work in these organizations has allowed him to advance his research and contribute to innovative solutions in the field.
Collaborations
Heidenreich has collaborated with several esteemed colleagues, including Hans-Peter Vornlocher and Philipp Hadwiger. These collaborations have further enriched his research and development efforts.
Conclusion
Olaf Heidenreich's contributions to the field of molecular biology through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in therapeutic strategies for serious diseases.