Haifa, Israel

Ofer Klein


 

Average Co-Inventor Count = 6.0

ph-index = 5

Forward Citations = 86(Granted Patents)


Company Filing History:


Years Active: 1993-2003

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10 patents (USPTO):Explore Patents

Title: Ofer Klein: Innovator in Chelation Therapy and Diagnostic Agents

Introduction

Ofer Klein is a prominent inventor based in Haifa, Israel, known for his significant contributions to the field of medical therapy and diagnosis. With a total of 10 patents, Klein has developed innovative compounds that have the potential to revolutionize the management of diseases associated with excess first transition series elements in the body.

Latest Patents

Klein's latest patents include groundbreaking inventions such as "Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis." This invention focuses on the synthesis and application of compounds that can effectively decrease the bioavailability of first transition series elements in vivo. These compounds are particularly useful in treating conditions related to excess elements, as they inhibit cell replication in mammalian, bacterial, and fungal cells. Additionally, they can be combined with radioisotopic or paramagnetic cations for use as diagnostic agents in nuclear medicine and MRI.

Another notable patent involves "Processes for synthesis of cyclic and linear polyamine chelators containing N-monosubstituted coordinating arms." This process allows for the cyclization of polyamines, enhancing their ability to coordinate with metal cations. The innovative methods described in this patent provide a significant advancement over previous techniques, ensuring higher efficiency in the synthesis of these important compounds.

Career Highlights

Throughout his career, Ofer Klein has worked with various companies, including Concat Ltd. and Chelator LLC. His work has focused on developing advanced chelation therapies and diagnostic agents that address critical medical challenges. Klein's expertise in this field has positioned him as a leading figure in the innovation of therapeutic solutions.

Collaborations

Klein has collaborated with notable individuals in his field, including Harry S. Winchell and Joseph Y. Klein. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Ofer Klein's innovative work in chelation therapy and diagnostic agents has made a significant impact on medical science. His patents reflect a commitment to improving health outcomes through advanced therapeutic solutions. Klein's contributions continue to pave the way for future innovations in the field.

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