Ofelia Barletta-Chacon

Title: Ofelia Barletta-Chacon: Innovator in Mycobacterial Research

Introduction

Ofelia Barletta-Chacon is a prominent inventor based in Lincoln, NE (US). She has made significant contributions to the field of microbiology, particularly in the study of mycobacteria. Her work focuses on the development of innovative solutions for combating pathogenic mycobacterial infections.

Latest Patents

Ofelia holds a patent for "D-alanine racemase mutants of mycobacteria and uses therefore." This invention is directed towards D-alanine racemase mutants of mycobacterial species. The D-alanine racemase gene (alrA) plays a crucial role in the synthesis of D-alanine, a fundamental component of peptidoglycan that forms the backbone of the bacterial cell wall. The patent also outlines methods for creating live-attenuated vaccines against pathogenic mycobacteria using these alrA mutants. Additionally, it describes the use of alrA mutants in screening for antimycobacterial agents that work synergistically with peptidoglycan inhibitors. Furthermore, the invention aims to identify new pathways of D-alanine biosynthesis for developing new drugs targeting peptidoglycan biosynthesis in mycobacteria and vaccines against pathogenic mycobacteria. Ofelia has 1 patent to her name.

Career Highlights

Ofelia Barletta-Chacon is affiliated with the University of Nebraska, where she conducts her research. Her work has garnered attention for its potential impact on public health, particularly in the development of vaccines and treatments for mycobacterial diseases.

Collaborations

Ofelia collaborates with her coworker, Raul Barletta, to advance research in her field. Their partnership has contributed to the innovative approaches being developed at the University of Nebraska.

Conclusion

Ofelia Barletta-Chacon is a dedicated inventor whose work in mycobacterial research holds promise for future medical advancements. Her contributions to the field are significant and continue to inspire further innovation.