Company Filing History:
Years Active: 2015-2024
Title: Nupura S Bhise: Innovator in Degradable Polymers for Gene Delivery
Introduction
Nupura S Bhise is a prominent inventor based in Baltimore, MD (US). She has made significant contributions to the field of polymer science, particularly in the development of degradable cationic polymers for gene delivery applications. With a total of 3 patents, her work is paving the way for advancements in cancer therapeutics and regenerative medicine.
Latest Patents
One of her latest patents involves the synthesis of multicomponent degradable cationic polymers. These polymers are designed to self-assemble with DNA, forming particles that are effective for gene delivery. Notably, small changes in polymer synthesis conditions, particle formulation conditions, and polymer structure can lead to significant variations in efficacy, which is dependent on the cell type. The polymers developed by Bhise have demonstrated greater effectiveness than commercially available materials, such as LIPOFECTAMINE 2000™, FUGENE®, or polyethylenimine (PEI), particularly for gene delivery to cancerous fibroblasts and human primary fibroblasts. The materials disclosed in her patents hold promise for applications in cancer therapeutics and regenerative medicine.
Career Highlights
Nupura S Bhise is affiliated with The Johns Hopkins University, where she continues her research and innovation in polymer science. Her work is characterized by a commitment to improving gene delivery systems, which can have a profound impact on medical treatments.
Collaborations
Throughout her career, Bhise has collaborated with notable colleagues, including Jordan J Green and Joel Chaim Sunshine. These collaborations have further enhanced her research and contributed to the advancement of her innovative projects.
Conclusion
Nupura S Bhise is a trailblazer in the field of degradable polymers, with her inventions poised to make significant contributions to gene delivery and cancer treatment. Her ongoing research at The Johns Hopkins University continues to inspire advancements in medical science.
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