Company Filing History:
Years Active: 2010
Title: Noureddine Fahmi: Innovator in Cyclodextrin Derivatives
Introduction
Noureddine Fahmi is a notable inventor based in Charlottesville, VA (US). He has made significant contributions to the field of chemistry, particularly through his innovative work on cyclodextrin derivatives. With a total of 2 patents, his inventions focus on addressing critical health challenges.
Latest Patents
Fahmi's latest patents include groundbreaking work on β-cyclodextrin derivatives. The first patent provides low molecular weight compounds that block the pore formed by protective antigen and inhibit anthrax toxin action. The structures of these compounds are derivatives of β-cyclodextrin. Per-substituted alkylamino derivatives displayed inhibitory activity and were protective against anthrax lethal toxin action at low micromolar concentrations. Additionally, the addition of one of the alkylamino derivatives to the bilayer lipid membrane with multiple PA channels caused a significant decrease in membrane conductance. Thus, this invention also provides methods for protection against anthrax toxicity. The second patent introduces β-cyclodextrin derivatives as antibacterial agents. This invention offers a new class of antibiotics to which pathogenic bacteria have not been exposed, and thus should not have developed resistance. These antibiotics are derivatives of β-cyclodextrin, a cyclic molecule comprising seven D-glucose units.
Career Highlights
Throughout his career, Fahmi has worked with various companies, including Innovative Biologics, Inc. and Pinnacle Pharmaceuticals, Inc. His work has been instrumental in advancing the understanding and application of cyclodextrin derivatives in medical science.
Collaborations
Fahmi has collaborated with notable individuals in his field, including Sidney M. Hecht and Vladimir Karginov. These collaborations have further enriched his research and contributions to the scientific community.
Conclusion
Noureddine Fahmi's innovative work on cyclodextrin derivatives has the potential to significantly impact health and medicine. His patents reflect a commitment to developing solutions for serious health threats, showcasing his role as a leading inventor in this field.