Norihiro Tada

Title: Norihiro Tada: Innovator in Transgenic Research

Introduction

Norihiro Tada is a prominent inventor based in Kawagoe, Japan. He has made significant contributions to the field of transgenic research, particularly in the development of animal models for studying human diseases. With a total of 2 patents, Tada's work has implications for understanding complex conditions such as Alzheimer's disease and metabolic bone diseases.

Latest Patents

Tada's latest patents include a transgenic mouse expressing a beta-Amyloid transgene. This invention relates to an animal model of human Alzheimer's disease, which is useful for determining the mechanisms of the disease and for developing potential therapeutic drugs. The transgenic mice are designed to overexpress a portion of the beta-amyloid precursor protein (APP) in various types of animal tissues. Another significant patent involves transgenic mice as a model for metabolic bone diseases. These mice carry a recombinant DNA construct comprising the gene encoding diphtheria toxin A chain, operably linked to an osteocalcin promoter. This model is particularly valuable as it exhibits decreased bone mass associated with a marked reduction in the number of osteoblasts.

Career Highlights

Norihiro Tada is currently associated with Hoechst Japan Limited, where he continues to advance his research in transgenic technologies. His work has garnered attention for its potential applications in therapeutic development and disease modeling.

Collaborations

Tada has collaborated with notable colleagues in his field, including Masahiro Sato and Takashi Kobayashi. These collaborations have further enriched his research and contributed to the advancement of transgenic studies.

Conclusion

Norihiro Tada's innovative work in transgenic research has positioned him as a key figure in the study of human diseases. His patents reflect a commitment to understanding complex biological processes and developing models that can lead to therapeutic advancements.