The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 1998
Filed:
Apr. 25, 1995
Applicant:
Inventors:
Norihiro Tada, Kawagoe, JP;
Masahiro Sato, Kawagoe, JP;
Takashi Kobayashi, Fukuoka, JP;
Toru Ikeda, Narashino, JP;
Katsuiku Hirokawa, Tokyo, JP;
Assignee:
Hoechst Japan Limited, Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
800-2 ; 435 697 ; 435 691 ; 4351723 ; 435 912 ; 424-92 ; 536 231 ; 536 234 ; 536 235 ; 536 241 ;
Abstract
Transgenic mice carrying a recombinant DNA construct comprising the gene encoding diphtheria toxin A chain operably linked to a osteocalcin promoter. The transgenic mice can be used as a model for metabolic bone diseases since they have decreased bone mass associated with a marked reduction in the number of osteoblasts.