Location History:
- Kronberg/Ts., DE (1988 - 1989)
- Kronberg, DE (1984 - 1993)
- Kronberg/Taunus, DE (2006)
Company Filing History:
Years Active: 1984-2006
Title: Norbert Kothe: Innovator in Immunology and Chromatography
Introduction
Norbert Kothe is a distinguished inventor based in Kronberg, Germany, known for his significant contributions to the fields of immunology and chromatography. With a total of nine patents to his name, Kothe has made remarkable advancements in the fractionation of plasma and serum, as well as the development of immunoglobulin preparations.
Latest Patents
Kothe's latest patents include a method for the chromatographic fractionation of plasma or serum, which focuses on separating albumin and immunoglobulin fractions using hydrophobic interaction chromatography. This innovative method employs an incremental salt gradient, particularly an ammonium sulfate buffer, to achieve effective fractionation. Another notable patent is for an intravenously administrable polyclonal immunoglobulin preparation designed for the treatment and prevention of bacterial infections. This preparation contains at least 50% by weight of IgM and is characterized by low anticomplementary activity, stability in aqueous solution, and freedom from viruses.
Career Highlights
Throughout his career, Kothe has worked with reputable companies such as Biotest Pharma GmbH and Biotest Serum-Institut GmbH. His work has significantly impacted the development of immunological therapies and chromatographic techniques, showcasing his expertise and dedication to advancing medical science.
Collaborations
Kothe has collaborated with notable colleagues, including Dieter Rudnick and Bertram Eichentopf, contributing to various projects that have furthered research in his field.
Conclusion
Norbert Kothe's innovative work in chromatography and immunology has led to significant advancements in medical treatments and research methodologies. His contributions continue to influence the scientific community and improve patient care.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.