Nirmal Kishor Yadav

Title: Nirmal Kishor Yadav: Innovator in Enantioselective Resolution Processes

Introduction

Nirmal Kishor Yadav is a notable inventor based in Maharashtra, India. He has made significant contributions to the field of chemistry, particularly in the development of processes for drug resolution. His innovative work has led to the creation of a patented method that enhances the efficiency of separating enantiomers in pharmaceutical applications.

Latest Patents

Nirmal Kishor Yadav holds a patent for an "Enantioselective resolution process for arylpropionic acid drugs." This invention relates to a novel non-catalytic enantioselective resolution process for the separation of enantiomers of arylpropionic acid drugs from racemic mixtures. The process involves dissolving the racemic mixture in an organic solvent and reacting it with an aqueous phase containing an ionic surfactant, with or without a suitable co-surfactant, and an electrolyte in a microemulsion, micellar, or biphasic medium. The mixture is then reacted with an appropriate chiral amine at temperatures ranging from 0 to 70 degrees Celsius to obtain a diastereomeric salt. The diastereomeric salt is subsequently acid hydrolyzed to yield the pure enantiomer of the drug, which can be extracted using known methods. Nirmal Kishor Yadav has 1 patent to his name.

Career Highlights

Nirmal Kishor Yadav is associated with the Council of Scientific and Industrial Research, where he has been involved in various research projects. His work focuses on enhancing the efficiency of drug resolution processes, which is crucial for the pharmaceutical industry. His innovative approach has garnered attention and recognition in the scientific community.

Collaborations

Nirmal Kishor Yadav has collaborated with notable colleagues such as Bhaskar Dattatraya Kulkarni and Ramdas Bhagvan Khomane. These collaborations have contributed to the advancement of research in the field of enantioselective processes.

Conclusion

Nirmal Kishor Yadav's contributions to the field of chemistry, particularly in enantioselective resolution processes, highlight his innovative spirit and dedication to advancing pharmaceutical science. His patented methods are a testament to his expertise and commitment to improving drug resolution techniques.