Nina Bacher Reuven

Title: Nina Bacher Reuven: Innovator in Viral Recombinases

Introduction

Nina Bacher Reuven is a prominent inventor based in Bloomfield, CT (US). She has made significant contributions to the field of molecular biology, particularly in the development of viral recombinases. With a total of 2 patents, her work has implications for genetic engineering and therapeutic applications.

Latest Patents

One of her latest patents focuses on viral recombinases, specifically related to the Herpes simplex virus (HSV). This invention includes a purified or isolated alkaline nuclease and a single-stranded DNA binding protein. In HSV-1, the alkaline nuclease is identified as the UL12 protein, while the single-stranded DNA binding protein is the ICP8 protein. The HSV recombinase can be utilized for various methods, including cloning, treating cells and organisms, and producing transgenic animals. Additionally, she has developed methods for replicating a DNA molecule to repair DNA lesion damage or for mutagenesis. This involves the use of UmuC, a translesion replication DNA polymerase that operates in the presence of UmuD', RecA, and SSB through damaged DNA molecules.

Career Highlights

Nina has worked with notable organizations such as Yeda Research and Development Company and the University of Connecticut. Her experience in these institutions has allowed her to advance her research and contribute to significant scientific discoveries.

Collaborations

Throughout her career, Nina has collaborated with esteemed colleagues, including Zvi Livneh and Guy Tomer. These partnerships have enriched her research and expanded the impact of her inventions.

Conclusion

Nina Bacher Reuven is a trailblazer in the field of viral recombinases, with her innovative patents paving the way for advancements in genetic research and therapeutic applications. Her contributions continue to influence the scientific community and inspire future innovations.