The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2001

Filed:

Sep. 12, 2000
Applicant:
Inventors:

Zvi Livneh, Rehovot, IL;

Nina Bacher Reuven, Bloomfield, CT (US);

Guy Tomer, Portland, OR (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 1/934 ; C12Q 1/68 ;
U.S. Cl.
CPC ...
C12P 1/934 ; C12Q 1/68 ;
Abstract

UmuC is found to be a translesion replication DNA polymerase which replicates in the presence of UmuD′, RecA and SSB through a DNA lesion of damaged DNA molecule and which is found to be highly mutagenic during in vitro gap-filling replication. A method for replicating a DNA molecule with DNA lesion damage and a method for mutagenesis of a DNA molecule are provided.


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