Nikolaus Müller

Title: Nikolaus Müller: Innovator in Pyrazole Chemistry

Introduction

Nikolaus Müller is a prominent inventor based in Monheim, Germany. He has made significant contributions to the field of chemistry, particularly in the development of methods for preparing pyrazole derivatives. With a total of 2 patents, Müller has established himself as a key figure in his area of expertise.

Latest Patents

Müller's latest patents include innovative methods for preparing 1-alkyl-pyrazol-5-carboxylic acid esters. The first patent describes a method where 1-alkyl-pyrazole-5-carboxylic esters are obtained with surprisingly low proportions of 1-alkyl-pyrazole-3-carboxylic esters. This is achieved by reacting a 2,4-diketo ester and/or an enolate thereof with an alkylhydrazine and/or a corresponding alkylhydrazinium salt, in the presence of a solvent and/or water, ensuring that free alkylhydrazine is present for at least 90% of the reaction. The second patent outlines a similar process, allowing for the economical preparation of 1-alkyl-pyrazole-5-carboxylic esters with limited formation of undesirable isomers.

Career Highlights

Nikolaus Müller is currently associated with Bayer Aktiengesellschaft, a leading global company in the pharmaceutical and life sciences sector. His work at Bayer has allowed him to focus on innovative chemical processes that have practical applications in various industries.

Collaborations

Müller collaborates with Michael Matzke, contributing to the advancement of research and development in their field. Their partnership has fostered a productive environment for innovation and discovery.

Conclusion

Nikolaus Müller is a distinguished inventor whose work in pyrazole chemistry has led to valuable patents and advancements in the field. His contributions continue to influence the industry and inspire future innovations.