Niels Witzke

Title: Niels Witzke: Innovator in Guanidine Derivatives

Introduction

Niels Witzke is a notable inventor based in New Brunswick, NJ (US). He has made significant contributions to the field of pharmaceuticals, particularly through his innovative work on guanidine derivatives of polyene macrolides. His research has the potential to impact various therapeutic applications.

Latest Patents

Witzke holds a patent for "Water-soluble guanidine derivatives of polyene macrolides and the esters." This patent involves the preparation of new guanidine derivatives of polyene macrolides that possess at least one free amino group and one free carboxy group. The derivatives include well-known compounds such as nystatin, pimaricin, amphotericin B, candicidin, and trichomycin. The process involves reacting the macrolide with a carbodiimide of a specific formula, showcasing Witzke's innovative approach to enhancing the solubility and efficacy of these compounds.

Career Highlights

Witzke is associated with A/S Dumex, also known as Dumex Ltd. His work at this company has allowed him to focus on the development of pharmaceutical innovations that address critical health challenges. His dedication to research and development has positioned him as a key figure in his field.

Collaborations

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Conclusion

Niels Witzke's contributions to the field of pharmaceuticals through his patent on guanidine derivatives highlight his innovative spirit and commitment to advancing medical science. His work continues to pave the way for new therapeutic options.