This inventor holds 3 USPTO granted patents. Top assignee: The Perkin-Elmer Corporation. Active years: 1999-2000.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1999-2000
Title: Nicole M Ellis: Innovator in Oligonucleotide Technology
Introduction
Nicole M Ellis is a prominent inventor based in San Mateo, CA (US). She has made significant contributions to the field of oligonucleotide technology, holding a total of 3 patents. Her work focuses on novel chimeric phosphoramidate oligonucleotides and their applications in DNA sequencing and nucleic acid amplification.
Latest Patents
One of her latest patents is titled "Phosphoramidate-phosphodiester oligonucleotide chimera as primers." This invention relates to innovative chimeric phosphoramidate oligonucleotides that feature both N3'-phosphoramidate linkages and phosphodiester linkages. The invention outlines methods for primer extension using these chimeric oligonucleotides as primers in various applications, including PCR and polynucleotide sequencing reactions. The process involves annealing a chimeric phosphoramidate oligonucleotide primer to a polynucleotide template, followed by the extension of the primer through a DNA polymerase catalyzed reaction. The invention also includes compositions that enhance the binding affinity between the chimeric oligonucleotides and polynucleotide templates, utilizing divalent cations to stabilize the phosphoramidate linkages against hydrolysis at elevated temperatures.
Career Highlights
Throughout her career, Nicole has worked with notable companies, including PerkinElmer Corporation. Her expertise in oligonucleotide technology has positioned her as a key figure in the field, contributing to advancements in genetic research and diagnostics.
Collaborations
Nicole has collaborated with esteemed colleagues such as Robert G Kuimelis and Cheryl R Heiner, further enhancing her contributions to the scientific community.
Conclusion
Nicole M Ellis is a distinguished inventor whose work in oligonucleotide technology has paved the way for advancements in DNA sequencing and nucleic acid amplification. Her innovative patents and collaborations reflect her commitment to scientific progress and innovation.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile