Nicole M Alessandri-Haber

Nicole M Alessandri-Haber is a prominent inventor based in Rye, NY (US). She has made significant contributions to the field of biomedical research, particularly in the area of coagulation factors. With a total of 8 patents to her name, her work has advanced the understanding of humanized coagulation factor XII (F12) and its applications.

Latest Patents

Her latest patents focus on non-human animals comprising a humanized coagulation factor 12 locus. These patents detail non-human animal genomes, non-human animal cells, and methods for creating and utilizing these genomes and cells. The innovations include non-human animals that express a human coagulation factor XII protein or a chimeric coagulation factor XII protein. Additionally, methods are provided for using these animals to assess the in vivo efficacy of human-coagulation-factor-XII-targeting reagents, such as nuclease agents designed to target human F12. Furthermore, her patents describe a short isoform of F12 produced locally in the brain, along with methods for utilizing this isoform.

Career Highlights

Throughout her career, Nicole has worked with notable companies, including Regeneron Pharmaceuticals, Inc. and Regeneron Pharmaceuticals, Inc. Her expertise in the field has led to groundbreaking research and development in coagulation factors.

Collaborations

Nicole has collaborated with esteemed colleagues, including Lynn Macdonald and Andrew J Murphy. These partnerships have fostered innovation and contributed to her success in the field.

Conclusion

Nicole M Alessandri-Haber is a trailblazer in the research of coagulation factors, with a strong portfolio of patents that reflect her dedication to advancing medical science. Her work continues to have a significant impact on the understanding and treatment of coagulation disorders.

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