Nicole Brument

This inventor holds 3 USPTO granted patents and 2 published patent applications, plus 1 CIPO patent and 2 EPO patents. Top assignees: Association Francaise Contre Les Myopathies, Chu Nantes, National Institute of Health and Medical Research. Active years: 2021-2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Nicole Brument. Retrieved from https://idiyas.com/inventor/nicole-brument

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 3 (Patent Applications = 2)

% Patents Active = 100.0

CIPO Patents = 1 (Patent Applications = 1)

EPO Patents = 2 (Patent Applications = 4)

Average Co-Inventor Count = 1.0

ph-index = 1

Forward Citations = 4(Granted Patents)

Company Filing History:

3 out of 11

Association Francaise Contre Les Myopathies

National Institute of Health and Medical Research

patents

4. 3 out of 156

The University of Nantes

patents

where one patent can have more than one assignee

Years Active: 2021-2025

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3 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12351832 - Recombinant adeno-associated virus particle purification with multiple-step anion exchange chromatography (2025-07-08),

2. 11203740 - Recombinant adeno-associated virus particle purification with multiple-step anion exchange chromatography (2021-12-21),

3. 11021689 - Recombinant adeno-associated virus particle purification comprising an affinity purification step (2021-06-01),

Title: Innovations in Viral Vector Purification: The Contributions of Nicole Brument

Introduction

Nicole Brument is an accomplished inventor based in Nantes, France. She has made significant contributions to the field of biotechnology, particularly in the purification of recombinant Adeno-Associated Virus (rAAV) particles. With a total of three patents to her name, her work is pivotal in advancing gene therapy technologies.

Latest Patents

Nicole Brument's latest patents focus on methods for obtaining purified recombinant Adeno-Associated Virus particles. One of her notable inventions describes a multi-step anion exchange chromatography process. This method includes depth filtration of a cell lysate or culture supernatant, followed by two steps of anion-exchange chromatography and tangential flow filtration. The result is a highly purified preparation of rAAV particles, which are essential for various therapeutic applications.

Career Highlights

Throughout her career, Nicole has worked with esteemed institutions such as Université de Nantes and CHU Nantes. Her experience in these organizations has allowed her to develop and refine her innovative techniques in viral vector purification.

Collaborations

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Conclusion

Nicole Brument's contributions to the field of biotechnology through her innovative methods for purifying rAAV particles are noteworthy. Her work not only enhances the efficiency of gene therapy but also showcases the importance of innovation in medical research.

Profile summary based on public USPTO records.