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Years Active: 2021-2025
Title: Innovations in Viral Vector Purification: The Contributions of Nicole Brument
Introduction
Nicole Brument is an accomplished inventor based in Nantes, France. She has made significant contributions to the field of biotechnology, particularly in the purification of recombinant Adeno-Associated Virus (rAAV) particles. With a total of three patents to her name, her work is pivotal in advancing gene therapy technologies.
Latest Patents
Nicole Brument's latest patents focus on methods for obtaining purified recombinant Adeno-Associated Virus particles. One of her notable inventions describes a multi-step anion exchange chromatography process. This method includes depth filtration of a cell lysate or culture supernatant, followed by two steps of anion-exchange chromatography and tangential flow filtration. The result is a highly purified preparation of rAAV particles, which are essential for various therapeutic applications.
Career Highlights
Throughout her career, Nicole has worked with esteemed institutions such as Université de Nantes and CHU Nantes. Her experience in these organizations has allowed her to develop and refine her innovative techniques in viral vector purification.
Collaborations
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Conclusion
Nicole Brument's contributions to the field of biotechnology through her innovative methods for purifying rAAV particles are noteworthy. Her work not only enhances the efficiency of gene therapy but also showcases the importance of innovation in medical research.