This inventor holds 8 USPTO granted patents and 3 published patent applications. Top assignee: Other. Active years: 2011-2021.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
8 out of 834,513 Years Active: 2011-2021
Title: Innovations of Nicole Aurora Leal
Introduction
Nicole Aurora Leal is a prominent inventor based in Gainesville, Florida. She has made significant contributions to the field of biotechnology, particularly in the area of nucleic acid synthesis. With a total of eight patents to her name, her work has advanced the understanding and application of non-standard nucleotides in RNA synthesis.
Latest Patents
One of her latest patents is titled "Processes using nucleoside triphosphates with stable aminoxy groups." This invention claims processes that append a single nucleotide having a 3'-ONH moiety to the 3'-ends of an oligonucleotide primer using 3'-deoxynucleoside triphosphates that have, instead of a 3'-OH moiety, a 3'-ONH moiety. The nucleotides involved contain both standard and non-standard nucleobases, and a key claim limitation is that substantially no hydroxylamine is present in the solutions used in the claimed processes. Another notable patent is "Enzymatic processes for synthesizing RNA containing certain non-standard nucleotides." This invention relates to processes that transcribe DNA molecules containing non-standard nucleotides using variants of T7 RNA polymerase to produce RNA transcripts that include their complementary non-standard nucleotides.
Career Highlights
Throughout her career, Nicole has focused on innovative approaches to nucleic acid chemistry. Her work has not only expanded the scientific community's understanding of nucleotides but has also paved the way for new applications in genetic research and therapeutic development.
Collaborations
Nicole has collaborated with esteemed colleagues in her field, including Steven Albert Benner and Daniel Hutter. These partnerships have further enriched her research and contributed to the advancement of biotechnology.
Conclusion
Nicole Aurora Leal's contributions to the field of biotechnology through her innovative patents and collaborations highlight her role as a leading inventor. Her work continues to influence the landscape of nucleic acid research and applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile