Company Filing History:
Years Active: 2016-2019
Title: Nicolas Wolff: Innovator in Neuroscience
Introduction
Nicolas Wolff is a prominent inventor based in Paris, France. He has made significant contributions to the field of neuroscience, particularly through his innovative work on polypeptides that have potential applications in treating conditions affecting the central and peripheral nervous systems. With a total of 3 patents, his research is paving the way for advancements in medical treatments.
Latest Patents
Wolff's latest patents focus on high MAST2-affinity polypeptides and their uses. These polypeptides contain a cytoplasmic domain that ends with a MAST-2 binding domain, consisting of 11 to 13 residues. The first two residues are S and W, while the last four are Q, T, R, and L. These polypeptides exhibit a high affinity for the PDZ domain of the human MAST2 protein. The invention also encompasses polynucleotides, vectors, lentiviral particles, cells, and compositions that include these polypeptides. Furthermore, it addresses the use of these components in the treatment and prevention of diseases, disorders, or conditions that affect the central nervous system (CNS) and peripheral nervous system (PNS). Additionally, the invention explores molecular signatures of cellular genes to assess the neurosurvival and neuroprotection activity of various molecules.
Career Highlights
Throughout his career, Nicolas Wolff has worked with esteemed institutions such as Institut Pasteur and the Centre National de la Recherche Scientifique. His research has been instrumental in advancing our understanding of neurobiology and developing therapeutic strategies for neurological disorders.
Collaborations
Wolff has collaborated with notable colleagues, including Monique Lafon and Christophe Prehaud. These partnerships have further enriched his research and contributed to the scientific community's knowledge in the field.
Conclusion
Nicolas Wolff's innovative work in neuroscience, particularly his patents on high MAST2-affinity polypeptides, showcases his commitment to advancing medical science. His contributions are vital for the development of new treatments for neurological conditions, highlighting the importance of research and collaboration in this field.
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