This inventor holds 2 USPTO granted patents and 2 published patent applications, plus 1 CIPO patent and 3 EPO patents. Top assignees: Adaptive Biotechnologies Corporation, Commissariat a L'energie Atomique Et Aux Energies Alternatives, Immunid. Active years: 2014-2023.
Company Filing History:
1 out of 58 
1 out of 8,816 
1 out of 1 Years Active: 2014-2023
Title: Nicolas Pasqual: Innovator in Immunological Diversity Analysis
Introduction
Nicolas Pasqual is a notable inventor based in Grenoble, France. He has made significant contributions to the field of immunology, particularly in the analysis of T and B lymphocyte diversity. With a total of 2 patents, his work has implications for disease diagnosis and treatment follow-up.
Latest Patents
Pasqual's latest patents focus on methods for studying V(D)J combinatory diversity. The first patent describes a method for analyzing the diversity of T and/or B lymphocytes in an individual. This method utilizes the amplification of genomic DNA fragments through PCR multi-n-plexes, employing a combination of at least three primers. Each primer couple includes one that hybridizes upstream in a V or D gene and another that hybridizes downstream in a J gene. This approach allows for the amplification of fragments characteristic of distinct V-J or D-J rearrangements. The applications of this method are particularly relevant in the treatment follow-up and diagnosis of certain diseases. The second patent similarly addresses the measurement of immunological diversity and the evaluation of treatment effects through V(D)J diversity analysis.
Career Highlights
Throughout his career, Nicolas Pasqual has worked with prominent organizations such as Immunid and the Commissariat à l'Énergie Atomique et aux Énergies Alternatives. His experience in these institutions has furthered his research and innovation in immunological studies.
Collaborations
Pasqual has collaborated with various professionals in his field, including Sébastien Weisbuch. Their joint efforts have contributed to advancements in understanding immunological diversity.
Conclusion
Nicolas Pasqual's innovative work in the analysis of immunological diversity has positioned him as a key figure in the field. His patents reflect a commitment to improving disease diagnosis and treatment methodologies.