Company Filing History:
Years Active: 2013
Title: The Innovative Contributions of Nicolas Dzamko
Introduction
Nicolas Dzamko is a notable inventor based in Dundee, GB. He has made significant contributions to the field of medical research, particularly in the study of LRRK2, a protein associated with various neurodegenerative diseases. His work focuses on developing methods to identify modulators of LRRK2, which could lead to advancements in therapeutic strategies.
Latest Patents
Dzamko holds a patent titled "Methods for identifying modulators of LRRK2." This patent describes a method for assessing the effect of a test compound on LRRK2 in a cell-based system. The method includes steps such as evaluating the effect of exposing the cell-based system to the test compound on the phosphorylation state of Ser910 and/or Ser935 of LRRK2. Additionally, it involves assessing the binding of LRRK2 to a 14-3-3 polypeptide and the subcellular location of LRRK2. This innovative approach is considered useful for evaluating potential LRRK2 inhibitors in both cell-based and in vivo systems. Dzamko has 1 patent to his name.
Career Highlights
Nicolas Dzamko is affiliated with the Medical Research Council, where he conducts his research. His work has been instrumental in advancing the understanding of LRRK2 and its implications in neurodegenerative diseases. His research efforts contribute to the broader field of medical science, aiming to improve treatment options for patients.
Collaborations
Dzamko has collaborated with esteemed colleagues, including Dario Alessi and R Jeremy Nichols. These collaborations enhance the depth and impact of his research, fostering a collaborative environment that drives innovation.
Conclusion
Nicolas Dzamko's contributions to the field of medical research, particularly through his patent on LRRK2 modulators, highlight his role as an innovative inventor. His work continues to pave the way for future advancements in understanding and treating neurodegenerative diseases.