Company Filing History:
Years Active: 2021-2023
Title: Innovations of Nicolas C Pégard in Optogenetics
Introduction
Nicolas C Pégard is a prominent inventor based in Berkeley, CA (US). He has made significant contributions to the field of optogenetics, particularly through his innovative patents. With a total of 2 patents, Pégard's work focuses on advancing the capabilities of neural activation techniques.
Latest Patents
One of his latest patents is titled "Three-dimensional scanless holographic optogenetics with temporal focusing - Apparatus and methods for 3D-Scanless Holographic Optogenetics with Temporal focusing (3D-SHOT)." This invention allows for precise and simultaneous photo-activation of arbitrary sets of neurons within the addressable volume of a microscope. The patent also introduces soma-targeted (ST) optogenetic tools, ST-ChroME and IRES-ST-eGtACR1, which are optimized for multiphoton activation and suppression. The methods utilize point-cloud holography to position multiple copies of a temporally focused disc that matches the dimensions of a designated neuron's cell body. Experiments conducted in cultured cells, brain slices, and living mice demonstrate single-neuron spatial resolution, even when optically targeting randomly distributed groups of neurons in three-dimensional space.
Career Highlights
Nicolas C Pégard is affiliated with the University of California, where he continues to push the boundaries of research in optogenetics. His work has garnered attention for its innovative approach to neural activation, making significant strides in the understanding of neuronal behavior.
Collaborations
Pégard collaborates with notable researchers such as Laura Waller and Hillel Adesnik, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Nicolas C Pégard's contributions to optogenetics through his patents and research at the University of California highlight his role as a leading inventor in the field. His work not only advances scientific understanding but also opens new avenues for future research and applications.