Tyne and Wear, United Kingdom

Nicola J Curtin


Average Co-Inventor Count = 5.7

ph-index = 5

Forward Citations = 69(Granted Patents)


Company Filing History:


Years Active: 1998-2004

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7 patents (USPTO):Explore Patents

Title: Nicola J Curtin: Innovator in Cancer Treatment

Introduction

Nicola J Curtin, based in Tyne and Wear, GB, is an accomplished inventor with a remarkable portfolio of seven patents. Her innovative work primarily focuses on developing therapeutic compounds aimed at improving cancer treatment and other cell proliferation disorders.

Latest Patents

Nicola's most recent patents include two significant inventions. The first revolves around cyclin-dependent kinase inhibitors, disclosing a variety of pyrimidine derivatives capable of inhibiting cyclin-dependent kinases (CDKs). These inhibitors have the potential to be effective therapeutic agents for treating tumors or other disorders linked with cell proliferation. Notably, the binding mechanism of these compounds to CDK molecules differs from known inhibitors such as olomoucine and roscovitine.

The second patent details a method for enhancing the effectiveness of cytotoxic drugs or radiotherapy through quinazolinone compounds. This discovery includes a range of 3-oxybenzamide compounds and quinazolinone compounds that serve as potent inhibitors of the DNA repair enzyme, poly(ADP-ribose) polymerase (PARP). These compounds are instrumental for use alongside DNA-damaging cytotoxic drugs or radiotherapy to amplify their therapeutic effects.

Career Highlights

Throughout her career, Nicola J Curtin has been associated with notable companies, including Newcastle University Ventures Limited and Cancer Research Campaign Technology Limited. Her wealth of experience and expertise in cancer research has made her a valuable asset in the field of medical innovation.

Collaborations

Among her collaborators are prominent individuals like Roger J Griffin and Alan H Calvert. Their joint efforts have led to significant advancements in developing effective treatments against cancer, showcasing the value of collaborative research in overcoming complex health challenges.

Conclusion

Nicola J Curtin’s contributions to the field of cancer treatment through her innovative patents have established her as a leading inventor. Her dedication to improving therapeutic approaches continues to pave the way for advancements that may enhance patient care and health outcomes in the medical community.

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