Cleveland Heights, OH, United States of America

Nick Mario Cirino


Average Co-Inventor Count = 5.5

ph-index = 2

Forward Citations = 116(Granted Patents)


Company Filing History:


Years Active: 1999-2001

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2 patents (USPTO):Explore Patents

Title: Innovations by Nick Mario Cirino

Introduction

Nick Mario Cirino is an accomplished inventor based in Cleveland Heights, OH, with a notable contribution to the field of medical research through his innovations. He holds two patents that focus on methods for treating viral infections, specifically those caused by RNA viruses such as Respiratory Syncytial Virus (RSV). His work exhibits a deep understanding of molecular biology and virology.

Latest Patents

Cirino's latest patents revolve around RNase L activators and antisense oligonucleotides that are effective in treating RSV infections. One of the inventions pertains to methods of inhibiting infection by RNA viruses using complexes that combine an RNase L activator with an oligonucleotide capable of binding to a virus's genomic, antigenomic, or mRNA strands. This novel approach is aimed at targeting any negative strand RNA virus, demonstrating the versatility and potential of Cirino's work.

In another patent, Cirino focuses specifically on compounds and methods for addressing RSV infections. These compounds consist of an antisense segment complementary to a normally single-stranded area of the RSV antigenomic RNA strand, a linker, and an RNase L activator. Through forming a complex of activated RNase L and the antisense molecule, the method provides a promising alternative to conventional treatments like ribavirin, based on in vitro results.

Career Highlights

Throughout his career, Nick Mario Cirino has been associated with reputable institutions such as The Cleveland Clinic Foundation and government laboratories. His contributions to virology and RNA research have solidified his reputation as an innovative thinker and researcher.

Collaborations

Cirino has collaborated with prominent figures in the scientific community, including Paul F. Torrence and Robert H. Silverman. These partnerships highlight his ability to work effectively with others in pursuit of significant medical advancements.

Conclusion

Nick Mario Cirino's inventive work represents a substantial advancement in the treatment of viral infections. His patents reflect a unique blend of scientific knowledge and creativity, marking him as a key player in the ongoing battle against RNA viral diseases.

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