This inventor holds 2 USPTO granted patents. Top assignees: Massachusetts Institute of Technology, Dartmouth College. Active years: 2005-2007.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Westwood, MA (US) (2005)
- Hanover, NH (US) (2007)
Company Filing History:
2 out of 8,586 
1 out of 708 
Years Active: 2005-2007
Title: Innovations and Contributions of Nicholas W. Shworak
Introduction
Nicholas W. Shworak is a notable inventor based in Hanover, NH (US). He has made significant contributions to the field of biomedical research, particularly in understanding and diagnosing myxomatous valvular disease. With a total of 2 patents, his work has implications for both animal models and therapeutic approaches.
Latest Patents
One of his latest patents is titled "Mouse model of myxomatous valvular disease." This invention provides an animal model that lacks heparan sulfate 3-O-sulfotransferase-1 activity, exhibiting characteristics associated with myxomatous valvular disease. This model is useful for identifying agents that can prevent, delay, or treat the disease. Additionally, methods for diagnosing myxomatous valvular disease are also included in this patent. Another significant patent is "Heparan sulfate D-glucosaminyl 3-O-sulfotransferases, and uses therefor." This patent discloses novel isolated nucleic acids and substantially pure protein preparations for naturally occurring and synthetic or chimeric heparan sulfate D-glucosaminyl 3-O-sulfotransferases (3-OSTs). The uses for these genes and proteins include the modification and sequencing of glycosaminoglycans.
Career Highlights
Throughout his career, Nicholas W. Shworak has worked with prestigious institutions such as the Massachusetts Institute of Technology and Dartmouth College. His research has focused on the molecular mechanisms underlying cardiovascular diseases, contributing to advancements in medical science.
Collaborations
Some of his notable coworkers include Robert D. Rosenberg and Jian Liu. Their collaborative efforts have furthered the understanding of heparan sulfate and its role in various biological processes.
Conclusion
Nicholas W. Shworak's innovative work and patents have significantly advanced the field of biomedical research, particularly in the context of myxomatous valvular disease. His contributions continue to influence the development of diagnostic and therapeutic strategies.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile