Nicholas Tilford

Title: The Innovations of Nicholas Tilford

Introduction

Nicholas Tilford is a notable inventor based in Hertfordshire, GB. He has made significant contributions to the field of medical research, particularly in the treatment of headache disorders and irritable bowel syndrome (IBS). With a total of 2 patents, his work has the potential to impact many lives.

Latest Patents

Tilford's latest patents include a method of identifying an inhibitor of the prostanoid EP4 receptor. This invention focuses on treating primary headache disorders, especially migraines, using antagonists of the EP receptor for prostaglandin E2. The patent highlights specific EP receptor antagonists, including azole compounds of formula (I). Another significant patent is an assay method for detecting 5-HT2B antagonists. This invention reveals that receptors for the neurotransmitter 5-HT are located on the human colon, and their activation can lead to abnormal motility and pain associated with IBS. The method provides a treatment approach for IBS by administering an effective amount of a 5-HT2B receptor antagonist.

Career Highlights

Throughout his career, Nicholas Tilford has worked with various companies, including Pharmagene Laboratories Limited and Asterand UK Acquisition Limited. His experience in these organizations has contributed to his expertise in the field of medical inventions.

Collaborations

Tilford has collaborated with notable individuals such as Richard A. Borman and Gordon Smith Baxter. These partnerships have likely enriched his research and development efforts.

Conclusion

Nicholas Tilford's innovative work in the medical field demonstrates his commitment to improving treatment options for patients suffering from migraines and IBS. His patents reflect a deep understanding of complex biological systems and a dedication to advancing medical science.