Gaithersburg, MD, United States of America

Nicholas Obiri


Average Co-Inventor Count = 4.0

ph-index = 3

Forward Citations = 140(Granted Patents)


Location History:

  • Gaithersburg, MD (US) (1997)
  • Gaithersberg, MD (US) (1999)
  • N. Potomac, MD (US) (2003)

Company Filing History:


Years Active: 1997-2003

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3 patents (USPTO):Explore Patents

Title: Innovations of Nicholas Obiri

Introduction

Nicholas Obiri is a notable inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of biotechnology, particularly in the development of chimeric proteins for targeted cancer therapies. With a total of 3 patents, his work focuses on innovative methods for delivering therapeutic agents to tumor cells.

Latest Patents

One of his latest patents is titled "IL-13 receptor specific chimeric proteins and uses thereof." This invention provides a method and compositions for specifically delivering an effector molecule to a tumor cell bearing an IL-13 receptor. The method involves providing a chimeric molecule that comprises an effector molecule attached to a circularly permuted IL-13 ("cpIL-13") that specifically binds an IL-13 receptor. The compositions include chimeric molecules comprising effector molecules such as modified Pseudomonas exotoxin attached to a cpIL-13. Another significant patent is also related to IL-13 receptor specific chimeric proteins, which are useful for killing tumor cells bearing IL-13 receptors. These molecules comprise a cytotoxic molecule attached to a targeting molecule that specifically binds an IL-13 receptor, with preferred targeting molecules including IL-13 and anti-IL-13R antibodies.

Career Highlights

Throughout his career, Nicholas Obiri has worked with esteemed organizations, including the United States of America as represented by the Department of Health and the National Institutes of Health, a component of the US Department of Health & Human Services. His work has been instrumental in advancing cancer treatment methodologies.

Collaborations

Nicholas has collaborated with notable professionals in his field, including Raj K Puri and Waldemar Debinski. These collaborations have contributed to the development of innovative solutions in cancer therapy.

Conclusion

Nicholas Obiri's contributions to the field of biotechnology through his patents and collaborations highlight his commitment to advancing cancer treatment. His innovative approaches continue to pave the way for new therapeutic strategies.

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