Nicholas Keen

Title: The Innovative Contributions of Nicholas Keen

Introduction

Nicholas Keen is a notable inventor based in Carlisle, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of peptide ligands. With a total of 3 patents, his work focuses on innovative solutions for medical applications.

Latest Patents

One of Nicholas Keen's latest patents is titled "Bicyclic peptide ligands specific for Nectin-4." This invention relates to polypeptides that are covalently bound to molecular scaffolds, allowing for the formation of two or more peptide loops. These peptides are designed to be high-affinity binders of Nectin-4, and the invention includes drug conjugates that can be used in preventing, suppressing, or treating diseases mediated by Nectin-4.

Another significant patent is "Bicyclic peptide ligands specific for OX40." Similar to his previous work, this invention involves polypeptides that bind to OX40. It also describes multimeric binding complexes that act as functional agonists of OX40. The patent encompasses drug conjugates and pharmaceutical compositions that utilize these peptide ligands and complexes for therapeutic purposes.

Career Highlights

Nicholas Keen is associated with Bicycletx Limited, where he continues to innovate in the field of peptide research. His work has the potential to impact various medical treatments and improve patient outcomes.

Collaborations

Nicholas collaborates with talented individuals such as Kevin McDonnell and Peter U Park. Their combined expertise contributes to the advancement of their projects and the success of their innovations.

Conclusion

Nicholas Keen's contributions to biotechnology through his innovative patents demonstrate his commitment to advancing medical science. His work on peptide ligands showcases the potential for new therapeutic approaches in treating diseases.