Nicholas C Masiello

Title: **The Innovative Contributions of Nicholas C. Masiello**

Introduction

Nicholas C. Masiello, a talented inventor based in Milford, Massachusetts, has made significant contributions to the field of biotechnology. With two patents to his name, his work focuses on advancing methods in protein purification and the production of human erythropoietin, a critical hormone used in various medical treatments.

Latest Patents

Masiello's first patent addresses a method for protein purification. This innovative technique involves removing an organic solvent from a mixture containing a compound with a polypeptide segment and the organic solvent. The process consists of contacting the mixture with an ion exchange resin under conditions that facilitate the compound's bonding to the resin. Subsequently, the resin is washed with a first aqueous solution that elutes the organic solvent while ensuring the compound remains bound to the resin.

His second patent pertains to cell encoding recombinant human erythropoietin. This invention details a rodent epithelioid cell that has been transformed with a recombinant DNA vector containing a DNA sequence encoding human erythropoietin. The transformed cell is capable of producing glycosylated human erythropoietin, which plays a vital role in the treatment of anemia and other medical conditions.

Career Highlights

Throughout his career, Masiello has worked with reputable organizations such as Integrated Genetics, Inc. and Genzyme Corporation. His experience in these companies has allowed him to refine his skills as an inventor and contribute to advancements in the biotechnological field.

Collaborations

Masiello has collaborated with notable coworkers, including James R. Zabrecky and Anton K. Beck. Their combined expertise has fostered an environment of innovation and creativity, leading to successful patent applications and furthering research in biotechnology.

Conclusion

Nicholas C. Masiello's inventive spirit and dedication to advancing biotechnology have led to essential patents that contribute to scientific achievements. His work demonstrates the ongoing impact of innovation in improving medical therapies and treatment methods, positioning him as a noteworthy figure in the field of inventors.