Company Filing History:
Years Active: 1989-1992
Title: Innovations of Nicholaos K Harakas
Introduction
Nicholaos K Harakas is a notable inventor based in Chesterfield, MO (US). He has made significant contributions to the field of biotechnology, particularly in the area of plasminogen activators. With a total of 3 patents to his name, his work has had a considerable impact on medical research and applications.
Latest Patents
One of his latest patents focuses on the large-scale production of plasminogen activator from normal human colon cells. This innovation allows for the cultivation of normal human colon cells that are adaptable to large-scale production. A purified tissue plasminogen activator (t-PA) is obtained from CCD-18Co normal human colon fibroblast cells, which demonstrates chemical differences from Bowes melanoma t-PA. Another significant patent involves a monoclonal antibody that is specific for human colon fibroblast-derived t-PA. This antibody is useful for immunoaffinity chromatography purification of t-PA and for determining t-PA levels in biological samples.
Career Highlights
Nicholaos K Harakas is associated with Monsanto Company, where he has been able to apply his expertise in biotechnology. His work has contributed to advancements in the understanding and application of plasminogen activators in medical science.
Collaborations
He has collaborated with notable coworkers such as Jon P Schaumann and Joseph Feder, further enhancing the research and development efforts in his field.
Conclusion
Nicholaos K Harakas is a distinguished inventor whose work in biotechnology has led to important advancements in the production and application of plasminogen activators. His contributions continue to influence the medical research landscape.