Ngan Fong Huang

Title: Innovations of Ngan Fong Huang

Introduction

Ngan Fong Huang is a prominent inventor based in Mountain View, California. She has made significant contributions to the field of biomedical imaging and regenerative medicine. With a total of two patents to her name, her work focuses on advanced imaging techniques and therapeutic devices.

Latest Patents

One of her latest patents is titled "High resolution imaging using near-infrared-II fluorescence." This invention discloses methods for imaging lumen-forming structures, such as blood vessels, using near-infrared fluorescence in the NIR-II region of 1000-1700 nm. The fluorescence is generated by exciting solubilized nanostructures, including carbon nanotubes, quantum dots, or organic molecular fluorophores attached to hydrophilic polymers. This innovative approach allows for fine anatomical vessel resolution down to -30 μm and high temporal resolution of 5-10 frames per second for small-vessel imaging, achieving up to 1 cm penetration depth in mouse hind limbs. This method compares favorably to traditional imaging modalities like CT and MRI, offering much higher spatial and temporal resolution.

Her second patent, "Graft for directed vascular and lymphatic regeneration and methods to guide endothelial cell assembly," relates to a therapeutic device comprising a collagen membrane with an aligned uniaxial or biaxial structure. This design enables mammalian cells plated on the membrane to align along the direction of the collagen fibrils. The graft can serve various purposes, including as a vascular prosthesis, a stent, or a nerve regeneration scaffold. Methods for preparing and implanting this graft are also provided.

Career Highlights

Ngan Fong Huang has worked with notable institutions, including Leland Stanford Junior University and Fibralign Corporation. Her work at these organizations has contributed to her expertise in the fields of imaging and regenerative medicine.

Collaborations

Throughout her career, she has collaborated with esteemed colleagues, including John P. Cooke and Guosong Hong. These collaborations have further enhanced her research and innovations in her field.

Conclusion

Ngan Fong Huang is a trailblazer in the realm of biomedical innovations, with her patents reflecting her commitment to advancing medical technology. Her contributions have the potential to significantly impact the fields of imaging and regenerative medicine.