Anaheim Hills, CA, United States of America

Nelson H Cooke


Average Co-Inventor Count = 2.3

ph-index = 2

Forward Citations = 27(Granted Patents)


Location History:

  • Concord, CA (US) (1987)
  • Anaheim Hills, CA (US) (1997 - 1999)

Company Filing History:


Years Active: 1987-1999

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3 patents (USPTO):Explore Patents

Title: Nelson H. Cooke: Innovator in Glycoprotein Profiling

Introduction

Nelson H. Cooke is a prominent inventor based in Anaheim Hills, CA (US). He has made significant contributions to the field of glycoprotein analysis, holding a total of 3 patents. His work focuses on methods for profiling oligosaccharides released from glycoproteins, which are crucial for understanding various biological processes.

Latest Patents

Cooke's latest patents include innovative methods for profiling oligosaccharides released from glycoproteins. These methods involve providing an analytical sample containing at least one released oligosaccharide and introducing it into an electrophoretic channel with a separation medium that has a pH less than 8 and greater than 2.5. By applying a sufficiently high electric field, the released oligosaccharides migrate and separate according to their molecular size or charge to mass ratio. This process allows for the detection of separated oligosaccharides, providing valuable glycoprotein conjugate profiling information. Preferred embodiments of these methods utilize a separation medium that includes lithium acetate buffer with a pH of about 4.75 and a gel of approximately 0.4% polyethylene oxide.

Career Highlights

Nelson H. Cooke is associated with Beckman Instruments, Inc., where he has been instrumental in advancing the technology related to glycoprotein profiling. His expertise and innovative approaches have positioned him as a key figure in this specialized field.

Collaborations

Throughout his career, Cooke has collaborated with notable colleagues, including Andras Guttman and John Harris. These collaborations have further enriched his research and contributed to the development of effective methodologies in glycoprotein analysis.

Conclusion

Nelson H. Cooke's contributions to the field of glycoprotein profiling through his patented methods highlight his innovative spirit and dedication to advancing scientific knowledge. His work continues to impact the understanding of glycoproteins and their roles in various biological systems.

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