Company Filing History:
5 out of 1,210 
2 out of 389 
1 out of 1,373 
Years Active: 2005-2010
Title: Nelly Malenkovich: Innovator in Immunology
Introduction
Nelly Malenkovich is a prominent inventor based in Boston, MA (US), known for her significant contributions to the field of immunology. With a total of 5 patents, her work focuses on advancing therapeutic methods that enhance immune responses.
Latest Patents
One of her latest patents is titled "Methods for upregulating an immune response with agents that inhibit the interaction between PD-L2 and PD-1." This invention provides isolated nucleic acid molecules, designated PD-L2 nucleic acid molecules, which encode novel B7-related molecules that act as ligands for PD-1. The invention also includes antisense nucleic acid molecules, recombinant expression vectors containing PD-L2 nucleic acid molecules, host cells that have been introduced to these expression vectors, and nonhuman transgenic animals with introduced or disrupted PD-L2 genes. Additionally, it offers isolated PD-L2 polypeptides, fusion proteins, antigenic peptides, and anti-PD-L2 antibodies. Furthermore, it provides methods for promoting or inhibiting the interaction between PD-L2 and PD-1, along with diagnostic and treatment methods utilizing the compositions of the invention.
Another significant patent is "B7-4 Antibodies and uses therefor." This invention presents isolated nucleic acid molecules, designated B7-4 nucleic acid molecules, which encode novel B7-4 polypeptides. It also includes antisense nucleic acid molecules, recombinant expression vectors containing B7-4 nucleic acid molecules, host cells that have been introduced to these expression vectors, and nonhuman transgenic animals with introduced or disrupted B7-4 genes. The invention further provides isolated B7-4 proteins, fusion proteins, antigenic peptides, and anti-B7-4 antibodies, along with diagnostic, screening, and therapeutic methods utilizing the compositions of the invention.
Career Highlights
Nelly has worked with esteemed organizations such as Dana-Farber Cancer Institute Inc. and Genetics Institute, Inc. Her innovative research has significantly impacted the field of cancer immunotherapy.
Collaborations
Some of her notable coworkers include Gordon James Freeman and Tatyana Chernova, who have contributed to her research endeavors.
Conclusion
Nelly Malenkovich's work in immunology exemplifies the importance of innovation in developing