Neil William Crowe

Title: Neil William Crowe and Immunotherapeutic Nanoparticle Innovation.

Introduction

Neil William Crowe is an inventor associated with Wake Forest University in Winston-Salem, North Carolina. His patent work concerns nanoparticle-based approaches for delivering therapeutic agents and supporting antitumor immune responses.

Latest Patents

Crowe is named on 1 patent, titled “Immunotherapeutic Nanoparticles and Methods Relating Thereto.” The patent describes compositions containing lipid nanoparticles and nucleic acid therapeutic agents. One example combines calcium phosphate nanoparticles containing a cyclic dinucleotide with a lipid coating that includes phosphatidylserine.

The disclosed compositions may be formulated for delivery to the lungs by inhalation or administered by injection. The patent also describes methods for treating lung cancer and other cancers. Its approach aims to deliver therapeutic agents, including cyclic dinucleotides, to antigen-presenting immune cells and elicit beneficial antitumor immunity.

Career Highlights

Crowe’s listed patent reflects research at the intersection of nanoparticle formulation, therapeutic delivery, and cancer immunotherapy. His affiliation with Wake Forest University connects this work to an academic research institution.

Collaborations

Dawen Zhao and Yang Liu are identified as Crowe’s coworkers. Their names are provided as professional associations, though specific roles in the patent are not stated in the supplied information.

Conclusion

Neil William Crowe’s patent documents a nanoparticle-based strategy for delivering immune-activating agents, with potential applications in lung cancer and other cancers.