Neil A Straus

Title: Neil A. Straus: Innovator in Polynucleotide Quantification

Introduction

Neil A. Straus is an accomplished inventor based in Emeryville, California, recognized for his significant contributions to the field of molecular biology. With a remarkable portfolio of 19 patents, his work primarily centers on innovative methods and compositions for identifying and quantifying polynucleotide sequences.

Latest Patents

One of Neil A. Straus's latest patents is titled "Methods, compositions, and kits comprising linker probes for quantifying polynucleotides." This invention focuses on the development of methods, reagents, kits, and compositions that facilitate the identification and quantification of target polynucleotide sequences. The patent describes a novel linker probe that consists of a 3′ target-specific portion, a loop, and a stem. When this probe is hybridized to a target polynucleotide, it generates a reaction product that includes a reverse primer portion and the stem nucleotides. The invention employs a detector probe alongside specific forward and reverse primers in an amplification reaction that allows for the detection of amplified target polynucleotides based on the introduced stem nucleotides. Moreover, the innovation enables the querying of a plurality of short microRNAs (miRNAs) with various linker probes, streamlining the decoding process in amplification reactions.

Career Highlights

Throughout his career, Neil has contributed his expertise to leading organizations, including Applied Biosystems, LLC, and Life Technologies Corporation. His innovative approach and profound understanding of molecular techniques have played a vital role in advancing the capacities of these companies in the biotechnology sector.

Collaborations

Neil's work has been enriched by collaborations with talented individuals such as Kai Qin Lao and Caifu Chen. These partnerships have fostered significant advancements in the methods used for polynucleotide quantification, further enhancing the impact of his inventions.

Conclusion

With a strong focus on innovation and a proven track record of successful patents, Neil A. Straus continues to be a leading figure in the field of molecular biology. His contributions not only advance scientific understanding but also provide essential tools for research and diagnostic applications in molecular genetics. As he progresses in his career, the impact of his work on the industry is expected to grow, inspiring future innovations in the field.