This inventor holds 4 USPTO granted patents and 3 published patent applications and 2 EPO patents. Top assignee: Ucbbiopharma Srl. Active years: 2021-2026.
Company Filing History:
Years Active: 2021-2026
Title: Neesha Dedi: Innovator in Protein Structure and Antibody Development
Introduction
Neesha Dedi is a prominent inventor based in Slough, GB. She has made significant contributions to the field of protein structure and antibody development, holding a total of 4 patents. Her work focuses on the human Gremlin-1 protein and its interactions with inhibitory antibodies.
Latest Patents
One of her latest patents is titled "GREMLIN-1 CRYSTAL STRUCTURE AND INHIBITORY ANTIBODY." This invention relates to crystals of the human Gremlin-1 protein and its complex with an inhibitory antibody. The invention also details the structure of human Gremlin-1, both independently and in complex with the antibody. It explores the uses of these structures in screening for agents that modulate Gremlin-1 activity. Additionally, the invention provides antibodies that bind to an allosteric inhibitory site on Gremlin-1, along with pharmaceutical compositions and medical applications of these antibodies and agents identified through the screening methods.
Career Highlights
Throughout her career, Neesha has worked with notable companies such as UCB Biopharma and Vertex Pharmaceuticals, Inc. Her expertise in the field has allowed her to make impactful advancements in protein research and therapeutic development.
Collaborations
Neesha has collaborated with esteemed colleagues, including Breda Twomey and David James McMillan. These partnerships have further enriched her research and innovation efforts.
Conclusion
Neesha Dedi's contributions to the field of protein structure and antibody development are noteworthy. Her innovative work continues to influence the scientific community and pave the way for future advancements in therapeutic applications.