Nazer K Khalaf

Title: Innovations by Nazer K Khalaf

Introduction

Nazer K Khalaf is an accomplished inventor based in Worcester, MA, with a notable portfolio of three patents. His work primarily focuses on advancements in protein crystallization and biocatalysis technology, contributing significantly to various fields including pharmaceuticals and cleaning agents.

Latest Patents

One of Khalaf's latest patents involves the development of controlled dissolution crosslinked protein crystals. These innovative protein crystals can transition from an insoluble and stable form to a soluble and active form, releasing protein activity at a controlled rate in response to environmental changes. Such changes may include variations in temperature, pH, chemical composition, or shear force. The crosslinked protein crystals exhibit a half-life activity under storage conditions that is at least twice that of the soluble protein from which they are derived. This technology has potential applications in protein delivery systems, cleaning agents, pharmaceuticals, vaccines, personal care products, and more.

Career Highlights

Khalaf is currently associated with Altus Biologics Inc., where he continues to innovate in the field of biocatalysis. His work emphasizes the use of crosslinked protein crystal formulations as catalysts in selective chemical reactions, particularly in organic solvents. This invention not only enhances the efficiency of chemical reactions but also optimizes processes used in industrial applications.

Collaborations

Khalaf collaborates with notable colleagues such as Alexey L Margolin and Rose A Persichetti, contributing to a dynamic research environment that fosters innovation and development.

Conclusion

Nazer K Khalaf's contributions to the field of protein crystallization and biocatalysis exemplify the impact of innovative thinking in science and technology. His patents reflect a commitment to advancing practical applications that benefit various industries.