This inventor holds 7 USPTO granted patents. Top assignee: Bio-Rad Laboratories, Inc.. Active years: 1976-1981.
Company Filing History:
Years Active: 1976-1981
Title: Nathan Lewin: Innovator in Immunoassay Technology
Introduction
Nathan Lewin is a distinguished inventor based in Corte Madera, CA (US). He has made significant contributions to the field of immunoassay technology, holding a total of 7 patents. His work has advanced the methods used in medical diagnostics, particularly in the detection of hormones and vitamins.
Latest Patents
One of Nathan Lewin's latest patents is the "Single-incubation two-site immunoassay." This invention provides a two-site immunoassay method for a ligand utilizing a single incubation. The multivalent ligand, labeled receptor for the ligand, and unlabeled receptor for the ligand covalently bound to a solid-phase support are incubated as a substantially stable suspension to produce a solid and liquid phase. The solid and liquid phases are separated from each other, and the labeled receptor in either phase is quantitated. This method may be used to assay for human thyroid-stimulating hormone using purified, radioactively labeled antibodies and unlabeled antibodies covalently bound to hydrolyzed polyacrylamide particles.
Another notable patent is the "Folate assay with ion exchange resin bound-free separation." This invention improves the competitive binding serum folate assay in which serum folate bound by folate-selective protein is separated from free serum folate by removal with an anion exchanger, preferably intermediate base anion exchange resin. The resins used are characterized by having an aliphatic lattice, particularly a polyalkyleneamine lattice having tertiary and quaternary amine groups. The resin is advantageously added for the separation function in tablet form.
Career Highlights
Nathan Lewin is currently associated with Bio-Rad Laboratories, Inc., where he continues to innovate in the field of immunoassays. His work has been instrumental in developing more efficient and accurate diagnostic tools that benefit the medical community.
Collaborations
Throughout his career, Nathan has collaborated with notable colleagues such as Henry J Jeong and Vito J Mangiardi. These collaborations have further enhanced the impact of his inventions in the industry.
Conclusion
Nathan Lewin's contributions to immunoassay technology exemplify the importance of innovation in medical diagnostics. His patents reflect a commitment to improving healthcare through advanced scientific methods.