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Years Active: 2015-2018
Title: Nathalie Y R Agar: Innovator in Single Cell Analysis
Introduction
Nathalie Y R Agar is a prominent inventor based in Newton, MA (US). He has made significant contributions to the field of single cell culture and analysis, holding a total of 3 patents. His work focuses on advancing methodologies that enhance the understanding of cellular behavior and composition.
Latest Patents
Agar's latest patents include innovative systems and methods for single cell culture and analysis by microscopy and MALDI mass spectrometry. These patents disclose techniques that isolate a plurality of cells in multiple wells, ensuring that a predetermined number of wells contain only one cell. This setup allows for optical interrogation of the cells and subsequent matrix-assisted laser desorption ionization of molecules within them. Another notable patent involves tissue sample preparation for MALDI MS imaging. This method combines matrix deposition with tissue fixation, enabling high-resolution spatial mapping of proteins, lipids, sugars, and nucleic acids. In some embodiments, the invention even relates to the fixation of whole organisms, allowing for direct mass spectrometry analysis.
Career Highlights
Throughout his career, Agar has worked with esteemed institutions such as Brigham and Women's Hospital, Inc. and Brandeis University. His experience in these organizations has contributed to his expertise in the field of mass spectrometry and cellular analysis.
Collaborations
Agar has collaborated with notable colleagues, including Jeffrey N Agar and J Christopher Love. These partnerships have likely enriched his research and innovation efforts.
Conclusion
Nathalie Y R Agar is a distinguished inventor whose work in single cell analysis and mass spectrometry has paved the way for advancements in biological research. His contributions continue to influence the scientific community and enhance our understanding of cellular dynamics.