The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Jun. 16, 2015
Applicants:

The Brigham and Women's Hospital, Boston, MA (US);

Massachusetts Institute of Technology, Boston, MA (US);

Inventors:

Nathalie Y. R. Agar, Newton, MA (US);

J. Christopher Love, Cambridge, MA (US);

Denis Loginov, Cambridge, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/04 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0418 (2013.01); G01N 21/648 (2013.01);
Abstract

Systems and methods for single cell culture and analysis by microscopy and matrix assisted laser desorption ionization mass spectrometry are disclosed. The systems and methods isolate a plurality of cells in a plurality of wells such that a predetermined number of the plurality of wells contain one and only one cell. The plurality of wells allow for optical interrogation of the cells and subsequent matrix assisted laser desorption ionizing of molecules within the cells.


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