Company Filing History:
Years Active: 2013
Title: Nathalie Boutonnet: Innovator in Peptide/Protein Complexes
Introduction
Nathalie Boutonnet is a distinguished inventor based in Rhode-St-Genese, Belgium. She has made significant contributions to the field of biochemistry, particularly in the area of peptide and protein interactions. Her innovative work has led to the development of a unique method for scoring the affinity of peptide/protein complexes.
Latest Patents
Nathalie holds a patent for a "Method for affinity scoring of peptide/protein complexes." This invention relates to a quantitative structure-based affinity scoring method that utilizes a highly specific force field function, such as CHARMM. The method operates on all-atom structural representations of peptide/receptor complexes. It scores peptide side-chain contributions to total affinity after detailed rotameric sampling and controlled energy refinement. Additionally, her method includes a de novo approach to estimate dehydration energies from simulations of individual amino acids in a solvent box filled with explicit water molecules.
Career Highlights
Nathalie is currently employed at Lonza Biologics Plc, where she continues to advance her research in biochemistry. Her work has garnered attention for its innovative approach to understanding peptide and protein interactions, which is crucial for various applications in drug development and biotechnology.
Collaborations
Nathalie has collaborated with notable colleagues, including Johan Desmet and Geert Meersseman. These partnerships have further enriched her research and contributed to the advancement of her innovative methods.
Conclusion
Nathalie Boutonnet is a pioneering inventor whose work in peptide/protein complexes has the potential to impact the field of biochemistry significantly. Her innovative methods and collaborations highlight her commitment to advancing scientific knowledge and applications in this vital area.