This inventor holds 3 USPTO granted patents and 1 published patent application. Top assignees: Purdue Research Foundation, The Salk Institute. Active years: 2003-2025.
Location History:
- Lafayette, IN (US) (2003)
- West Lafayette, IN (US) (2021)
Company Filing History:
3 out of 2,781 
1 out of 593 
Years Active: 2003-2025
Title: Innovations of Natalia Doudareva in Terpenoid Production
Introduction
Natalia Doudareva is a prominent inventor based in West Lafayette, Indiana, known for her significant contributions to the field of sustainable high-yield terpenoid production. With a total of three patents to her name, she has made remarkable strides in the development of transgenic plants that enhance terpenoid production.
Latest Patents
Doudareva's latest patents focus on methods and platforms for sustainable high-yield terpenoid production. These innovations involve transgenic plants that incorporate a first heterologous nucleic acid encoding a polypeptide with 3-hydroxy-3-methylglutaryl-CoA reductase activity. Additionally, a second heterologous nucleic acid is included, which facilitates the de novo formation of isopentenyl phosphate in the plant. This process can be achieved through the overexpression of phosphomevalonate decarboxylase alongside 3-hydroxy-3-methylglutaryl-CoA reductase, resulting in a potential 130-fold increase in terpenoid production compared to wild-type plants.
Career Highlights
Throughout her career, Doudareva has worked with esteemed organizations such as the Purdue Research Foundation and the Salk Institute for Biological Studies. Her work has been instrumental in advancing the understanding and application of terpenoid production in various industries.
Collaborations
Doudareva has collaborated with notable colleagues, including Joseph Noel and Laura Henry, contributing to the innovative research in her field.
Conclusion
Natalia Doudareva's work in terpenoid production exemplifies the intersection of innovation and sustainability. Her patents and collaborations highlight her commitment to advancing agricultural biotechnology.