Company Filing History:
Years Active: 2011-2012
Title: Naokatu Aoki: Innovator in Pharmaceutical Chemistry
Introduction
Naokatu Aoki is a prominent inventor based in Toyama, Japan. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of innovative processes for drug production. With a total of two patents to his name, Aoki's work is recognized for its potential impact on medical treatments.
Latest Patents
Aoki's latest patents include a process for the production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-OXO-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester. This process involves an intermediate that is a 6-(halomethyl)-1,2-benzisoxazol-3(2H)-one derivative. The formula specifies that R is a methyl group substituted with one or more optionally substituted phenyl groups or an optionally substituted oxygen-containing heterocyclic group, while X is a halogen atom. Another patent details a preparation method using the same intermediate, which allows for the safe and efficient production of 3-{5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6-yl)methoxy]phenyl}propionic acid. This compound is noted for its utility as an antirheumatic agent, achieved with a high yield.
Career Highlights
Aoki is currently employed at Toyama Chemical Co., Ltd., where he continues to innovate in the pharmaceutical sector. His work has been instrumental in advancing methods that enhance the efficiency and safety of drug production processes.
Collaborations
Throughout his career, Aoki has collaborated with notable colleagues, including Kenji Yonezawa and Tamotsu Takamatsu. These partnerships have contributed to the successful development of his patented processes and have fostered a collaborative environment for innovation.
Conclusion
Naokatu Aoki's contributions to pharmaceutical chemistry through his innovative patents highlight his role as a key inventor in the field. His work not only advances drug production methods but also holds promise for improving medical treatments.