Company Filing History:
Years Active: 1998-1999
Title: **Inventor Spotlight: Nanda D Sinha**
Introduction
Nanda D Sinha, an accomplished inventor based in Acton, MA, has made significant contributions to the field of biochemical innovations. With a portfolio that includes two patents, her work primarily focuses on chemical processes and methods that play a crucial role in modern molecular biology.
Latest Patents
Nanda's latest patents demonstrate her expertise in developing innovative chemical compounds and methods. The first patent, titled **"Activated esters of 1-phenylpyrazolin-5-one for labeling,"** details a process involving pyrazolinone derivatives for the non-radioactive labeling of amine-functionalized molecules. This invention holds promise for various biomolecules, including DNA, RNA, PNA, and peptides, allowing for enhanced labeling techniques through the activation of carboxyl-containing reporter groups such as biotin and fluorescein.
The second patent, **"Method of making 2'-O-alkyl pyrimidine ribonucleosides,"** outlines a systematic approach for producing 2'-O-derivatized ribonucleosides. This method enhances the synthesis of critical nucleic acid components by selectively derivatizing the 2'-hydroxyl group, leading to the production of partially protected nucleosides. Her innovative techniques contribute to the efficiency of RNA synthesis and expand the toolkit available for molecular biologists.
Career Highlights
Nanda D Sinha is currently employed at Perseptive Biosystems Inc., where she leverages her skills and expertise in molecular innovations. Her work is centered around enhancing biochemical methods that have wide applications in research and clinical settings, contributing to significant advancements in the life sciences.
Collaborations
Throughout her career, Nanda has collaborated with notable colleagues such as Richard P Hodge and Jonathan N Kremsky. These partnerships exemplify the importance of teamwork in the innovation process, as individual expertise is combined to achieve breakthroughs in biochemical research.
Conclusion
Nanda D Sinha's contributions to the field of biochemical inventions underscore her role as a key figure in the advancement of molecular technologies. Her innovative patents reflect a deep understanding of chemical processes and a commitment to enhancing scientific tools available for research. As she continues her work at Perseptive Biosystems Inc., her contributions may pave the way for further innovations in molecular biology.