Company Filing History:
Years Active: 2001-2003
Title: Nancy Lee: Innovator in Stereoselective Synthesis
Introduction
Nancy Lee is a prominent inventor based in Foxboro, MA (US). She has made significant contributions to the field of chemistry, particularly in the area of stereoselective synthesis. With a total of 2 patents to her name, her work has implications for the development of aminosterols and vitamin D analogs.
Latest Patents
One of Nancy Lee's latest patents focuses on the stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols and vitamin D analogs. This method describes the stereoselective reduction of an unsaturated alkyl ketone substituent attached to a fused ring base. In this innovative process, the unsaturated alkyl ketone reacts with a chiral oxazaborolidine reagent, leading to the formation of an unsaturated alkyl alcohol. This alcohol can be further reduced to yield a saturated alkyl alcohol if desired. The fused ring base can be a steroid ring base or a base of a vitamin D analog. This process can be applied to alkeneone or alkyneone substituents on a steroid ring base, facilitating the production of squalamine and other useful aminosterol compounds.
Career Highlights
Throughout her career, Nancy Lee has worked with notable companies such as Magainin Pharmaceuticals, Inc. and Ohr Pharmaceutical Inc. Her experience in these organizations has contributed to her expertise in the field of pharmaceutical chemistry.
Collaborations
Nancy has collaborated with several professionals in her field, including William Alvin Kinney and Steven Jones. These collaborations have enriched her research and development efforts.
Conclusion
Nancy Lee is a distinguished inventor whose work in stereoselective synthesis has advanced the field of chemistry. Her contributions continue to influence the development of important compounds in medicine.