This inventor holds 6 USPTO granted patents. Top assignee: Vertex Pharmaceuticals, Inc.. Active years: 1997-2000.
Company Filing History:
Years Active: 1997-2000
Title: Nancy L St Clair: Innovator in Protein Therapy
Introduction
Nancy L St Clair is a prominent inventor based in Charlestown, MA (US). She has made significant contributions to the field of protein therapy, holding a total of six patents. Her innovative work focuses on the development of methods for orally administering crosslinked proteins, which have various therapeutic applications.
Latest Patents
One of her latest patents involves a method of protein therapy by orally administering crosslinked proteins. This method includes immobilizing proteins such as enzymes or antibodies by crosslinking them with a multifunctional crosslinking agent. The crosslinked protein crystals can be lyophilized for storage, ensuring their stability and effectiveness. A preferred protein in this method is an enzyme, such as thermolysin, elastase, asparaginase, lysozyme, lipase, or urease. The crosslinked enzyme crystals retain at least 91% activity after incubation for three hours in the presence of a concentration of Pronase that causes the soluble uncrosslinked form of the enzyme to lose at least 94% of its initial activity. This innovative approach allows for the use of crosslinked enzyme or antibody crystals in various applications, including assays, diagnostic kits, biosensors, and therapeutic treatments.
Career Highlights
Nancy L St Clair has established herself as a key figure in the biotechnology industry. She is currently employed at Vertex Pharmaceuticals, Inc., where she continues to advance her research and development efforts in protein therapy. Her work has the potential to significantly impact the treatment of conditions related to pancreatic insufficiency and fat malabsorption.
Collaborations
Throughout her career, Nancy has collaborated with various professionals in her field. One notable coworker is Manuel A Navia, with whom she has worked closely on her innovative projects.
Conclusion
Nancy L St Clair's contributions to protein therapy exemplify her dedication to advancing medical science. Her innovative methods and patents are paving the way for new therapeutic options in the treatment of various health conditions.